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Gastroretentive Drug Delivery Systems: A Patent
Perspective
Mohamed G Dehghan and Furquan N Khan*
Dr Rafiq Zakaria Campus, Department of Pharmaceutics, Y.B.Chavan College
of Pharmacy, Dr Rafiq Zakaria Marg, Rauza Bagh,
Aurangabad.
(M.S) India
*For
Correspondence:
E-mail:
mhdehghan@hotmail.com or
furkhankhan@rediffmail.com
Received:
19-Nov-09
Revised:
03-Jan-09
Accepted:
07-Jan-09
International Journal of Health Research,
March
2009; 2(1):
23-44 (e215p33-54)
Review Article
Abstract
Patent, once seen as a
technical matter for legal experts, has today become a
central concern for governments, businesses, civil
society, scientists and innovators. In a world where the
economic growth of nations is driven increasingly by
creativity and knowledge of their people, effective
intellectual property (IP) systems, which create
incentives for innovation and structures for sharing the
results, are key to unlocking the human potentials.
Recent pharmaceutical patented literature has shown
increased interest in novel dosage forms that can be
retained in the stomach for a prolonged and predictable
period of time. Since the last three decades many drug
molecules formulated as Gastroretentive Drug Delivery
System (GRDDS) have been patented keeping in view its
commercial success. This review on GRDDS attempts to
compile the available patented literature with all the
possible mechanisms used to achieve gastric retention.
Keywords:
Gastric Retention,
Mechanism, Patents, Drugs, Polymers, Evaluation Method.
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