Anthelminthic Activity of Asta Churna
Devi K*,
Indumathy S, Rathinambal V,
Uma S,
Kavimani S and Balu V
Department of Pharmacology, Mother Theresa Post Graduate
and Research Institute of Health Sciences, Indira Nagar,
Gorimedu, Puducherry-605006
*For
Correspondence:
devikadir2000@yahoo.co.in,
indumathy85@gmail.com,
rathinambal_14@yahoo.co.in,
uma_mpharma@yahoo.co.in,
drskavimani@yahoo.co.in
Revised:
03-Nov-08 Accepted: 29-Dec-08
International Journal of Health Research,
March
2009; 2(1):
101-103 (e217p65-68)
Short Communication
Abstract
Purpose:
To determine the effect
of Asta churna (an ayurvedic preparation of
Impcops) on Indian earthworms.
Methods: Asta
churna (2.5 mg/mL and 5 mg/mL) were investigated for
activity in Indian earthworms (Pheretima postuma)
against piperazine citrate (15 mg/mL) and albendazole
(20 mg/mL) as standard references and normal saline as
control. The time to achieve paralysis of the worms was
determined.
Results:
The two concentrations
of Asta churna exhibited significant anthelminthic
activity (p < 0.001) when compared with the piperazine
citrate, albendazole and normal saline.
Conclusion:
Asta chuma has paralytic effect on Indian
earthworms.
Keywords:
Asta churna,
Pheretima postuma, Anthelminthic activity.