Advances in Iontophoresis for Drug
Delivery
MHG Dehghan, Md Ismail Mouzam*
Dept of Pharmaceutics, Y B
Chavan College of Pharmacy, Dr Rafiq zakaria campus,
Rauza bagh, Aurangabad-431001, Maharashtra State, India.
E-mail:
*For
Correspondence:
E-mail:
mdismail1111@rediffmail.com
Tel:
+9198604408576.
International Journal of Health Research,
September
2008; 1(3):
115-127
Received: 06-Jun-08 Revision
received: 26-Jun-08 Accepted for publication:
24-Jul-08
Review
Article
Abstract
Iontophoresis is an
exciting technology that was initially investigated 250
years ago. Simply defined, it is the application of an
electrical potential that maintains a constant electric
current across the skin or barrier that enhances the
delivery of ionized as well as unionized moieties. In
the past few years, different types of iontophoresis
such as transdermal, ophthalmic, transungual, buccal,
ural and transnasal iontophoresis have been reported.
Each system has its own advantages and drawbacks. The
review summarizes recent findings and applications of
various iontophoresis techniques.
Keywords:
Iontophoresis;
transdermal; ocular; buccal; transungual; ural; drug
delivery.